The best phone number to reach Lexmark Customer Service in the United States is **1-800-539-6275**. This number is the primary contact for addressing product issues, service requests, returns, replacements, and information, and is used by 91% of consumers contacting Lexmark[1][4]. Customer support representatives are also available by phone at **1-866-378-5646** Monday to Friday from 9:00 AM to 6:00 PM (EST) for general customer support inquiries[3].

For email contact, **privacy@lexmark.com** is used for customer concerns, and **solutions.support@lexmark.com** is available for technical support inquiries[1][4]. For order-related or ecommerce queries, the email **ecommerce@lexmark.com** and phone number **1-866-378-5646** are provided[3].

Lexmark offers comprehensive customer support including technical assistance, customized service programs, and genuine replacement parts to minimize downtime and costs[2]. Their global headquarters phone number is +1-859-232-2000[1][5], and they provide regional support numbers internationally[4][5].

In summary, for prompt US customer service contact:

– **Phone:** 1-800-539-6275 (best number for most issues)
– **Support hours:** Monday-Friday, roughly 9 AM to 6 PM EST
– **Email:** privacy@lexmark.com (general issues), solutions.support@lexmark.com (technical support)

Additional contact information and regional support can be found on Lexmark’s official website and support pages.